Coast Resorts Open Roads Forum: Around the Campfire: 2019–2022 CORONAVIRUS PANDEMIC POSTINGS
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 > 2019–2022 CORONAVIRUS PANDEMIC POSTINGS

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BCSnob

Middletown, MD

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Posted: 12/29/20 08:07am Link  |  Quote  |  Print  |  Notify Moderator

“ We will ALWAYS be playing catch-up with this one.....just like the flu virus, we'll be receiving new anti-covid vaccines probably forever.”

Maybe, maybe not. Mumps, measles, etc are also viruses which mutated like all other viruses; however, changes to the vaccines for these viruses have not been required in decades. Measles is a good example since it too is a highly contagious RNA virus spread by droplets in the air and on surfaces. There are 24 genotypes with 4 predominant variants in circulation.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518568/#sec1title

* This post was edited 12/29/20 08:16am by BCSnob *

pianotuna

Regina, SK, Canada

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Posted: 12/29/20 10:08am Link  |  Quote  |  Print  |  Notify Moderator

Perhaps we can learn a bit from history?

https://www.theglobeandmail.com/canada/a........cu_id=2cuyUfAhTCB%2BGdlk7Gu0QderjvixZT6G


Regards, Don
My ride is a 28 foot Class C, 256 watts solar, 556 amp-hours of Telcom jars, 3000 watt Magnum hybrid inverter, Sola Basic Autoformer, Microair Easy Start.

dturm

Lake County, IN

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Posted: 12/29/20 10:09am Link  |  Quote  |  Print  |  Notify Moderator

I'm confident that if mutations that affect vaccine efficacy happen our scientists will be able to modify the vaccines appropriately.

I'm a little more concerned about length of immunity as initial reports that the 1/2 life of neutralizing antibodies is a little shorter (especially in older people) than ideal. I hope we won't have to get revaccinated every 6 months. I'm sure details and differences between the various vaccines will become apparent as time goes on.

The main thing now is we apparently have a tool other than routine public health measures and precautions that could in time really end the epidemic.


Doug & Sandy
Kaylee (16-year-old Terrier of some sort)
Winnie 4 1/2 year old golden
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MEXICOWANDERER

las peñas, michoacan, mexico

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Posted: 12/29/20 12:41pm Link  |  Quote  |  Print  |  Notify Moderator

The only rational avenue is to let the Brits steam full speed ahead with their bare knuckle vaccine versus vaccine testing.

If synthetic derived vaccine provides superior efficacy and longevity versus conventionally derived serum, that in itself will prove to be a stunning game changer.

I am praying that a tsunami of success overwhelms the naysayers. We have them down here which is sad. Its indigenous factions in the extreme south. Outright public drama is very rare. But the proliferation is much higher than even in California. Perhaps ten times as intense near the border. They checked a Central American migrant camp in Tijuana and found 8.5 out of 10 migrants that tested positive. Our AZ vaccine starts distribution in six days. The Pfizer immunizations started a few weeks ago for medical personnel.

2020 please fade into history!

pianotuna

Regina, SK, Canada

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Posted: 12/29/20 02:17pm Link  |  Quote  |  Print  |  Notify Moderator

Hi Folks,

The University of Saskatchewan has just had a vaccine approved for human trials! https://www.cbc.ca/news/canada/saskatche........approved-human-clinical-trials-1.5856526

* This post was edited 12/29/20 03:44pm by an administrator/moderator *

BCSnob

Middletown, MD

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Posted: 12/29/20 04:18pm Link  |  Quote  |  Print  |  Notify Moderator

Colorado officials identify first known US case of COVID-19 variant seen in UK

First known (identified) case; since very little genotyping is being done on covid cases in the USA very little is known about the prevalence this variant in the USA.

MEXICOWANDERER

las peñas, michoacan, mexico

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Posted: 12/29/20 08:02pm Link  |  Quote  |  Print  |  Notify Moderator

I wonder if the Warp Speed Program has any bearing on other viral pathogen solutions like my personal Nighte H5N1 influenza? Or is the MERS viral strain utterly unique?

BCSnob

Middletown, MD

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Posted: 12/29/20 08:56pm Link  |  Quote  |  Print  |  Notify Moderator

Influenza (receptors containing sialic acid) and coronavirus (ACE2 receptor) enter cells by different pathways.

Quote:

Influenza viruses bind to receptors containing sialic acid on the cell surface.

Endocytosis of influenza viruses


Vaccines for SARS-CoV-2 may provide some protection (cross reactivity) against other coronaviruses because they target the portion of those viruses by which they enter cells; however, influenza viruses enter cells by a different pathway which the covid vaccines do not block.

* This post was edited 12/29/20 09:15pm by BCSnob *

MEXICOWANDERER

las peñas, michoacan, mexico

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Posted: 12/30/20 12:25am Link  |  Quote  |  Print  |  Notify Moderator

AZ vaccine officially approved in Great Britain
No mention of 1st jab strength.

Deb and Ed M

SW MI & Space Coast, FL USA

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Posted: 12/30/20 08:08am Link  |  Quote  |  Print  |  Notify Moderator

Good news/bad news: Brevard County health Dep't in FL announced that they are accepting folks aged 65+ for vaccination. One has to call and make an appointment for vaccination. Yay!!

The bad news: - yesterday, the phone lines were absolutely jammed. I tried a dozen times to get through.... Today, the phone number is "temporarily unavailable". I'm going to guess they figure they've already filled all available slots?

Sigh - I've managed to avoid getting Covid this long, I figure I can wait a while longer.

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