MEXICOWANDERER
las peñas, michoacan, mexico
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28 Sept. Data by Johns Hopkins
![[image]](https://ichef.bbci.co.uk/news/800/cpsprodpb/A010/production/_114667904_usmapcases_jh_28sep-nc.png)
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MEXICOWANDERER
las peñas, michoacan, mexico
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I asked this question openly on this forum months ago. And today Johns Hopkins provided an answer.
Today's Headlines: October 1, 2020
COVID-19
Clinical Practice
Efficacy and Safety of Hydroxychloroquine vs Placebo for Pre-exposure SARS-CoV-2 Prophylaxis Among Health Care Workers (JAMA Network) Among hospital-based HCWs at high risk of exposure to SARS-CoV-2, hydroxychloroquine, 600 mg, daily, for 8 weeks did not reduce the incidence of SARS-CoV-2 infection compared with placebo. Our findings are consistent with what is to our knowledge the only other randomized COVID-19 prophylaxis trial published to date.
THANK YOU J.A.M.A. and Johns Hopkins! Apparently folks took mine and other queries seriously. There is no reason to Rx hydroxychloroquine for off-label reasons freeing up inventory for legitimate autoimmune treatment.
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MEXICOWANDERER
las peñas, michoacan, mexico
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Deserving a separate entry. A coincidence? Verbatim from Johns Hopkins
Moderna Says Its Coronavirus Vaccine Won't Be Ready Until 2021 (Axios) Moderna CEO Stéphane Bancel said Wednesday that his company's coronavirus vaccine won't be available for widespread distribution until at least spring 2021, according to Financial Times. Why it matters: Bancel told FT that the drugmaker will not seek emergency authorization for FDA approval for its vaccine for front-line medical workers and at-risk individuals until Nov. 25 at the earliest.
Government Affairs & National Security
Exclusive: FDA Widens U.S. Safety Inquiry into AstraZeneca Coronavirus Vaccine (Reuters) The US Food and Drug Administration has broadened its investigation of a serious illness in AstraZeneca Plc’s COVID-19 vaccine study and will look at data from earlier trials of similar vaccines developed by the same scientists, three sources familiar with the details told Reuters. The widened scope of the FDA probe raises the likelihood of additional delays for what has been one of the most advanced COVID-19 vaccine candidates in development. The requested data was expected to arrive this week, after which the FDA would need time to analyze it, two of the sources said.
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pianotuna
Regina, SK, Canada
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Better that they "get it right" the first time than to rush into using an experimental vaccine.
Regards, Don
My ride is a 28 foot Class C, 256 watts solar, 556 amp-hours of Telcom jars, 3000 watt Magnum hybrid inverter, Sola Basic Autoformer, Microair Easy Start.
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JaxDad
Greater Toronto Area
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All of which is the stuff that scares the begeebers (yes, that’s a word, LOL) out of me with the ‘mostly accurate’ speedy tests.
Being only 2 or 3 percent off isn’t a big deal if you’re pointing a machine gun, dropping bombs or sexing chicken hatchlings.
In this case it IS a BIG deal.
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Fizz
Ottawa, Canada
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MEXICOWANDERER
This is from an interview I listened to on BBC.
I found the article and got bogged down very quickly.
Thought you might be interested.
https://science.sciencemag.org/content/early/2020/09/29/science.abd7672
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MEXICOWANDERER
las peñas, michoacan, mexico
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This is why any statistical study needs peer review. The people studied in the states of Tamil Nadu and Andhra Pradesh cannot be compared to first world countries. The disparity is enormous. Most, not merely many, children harbor chronic diseases, parasites, secondary effects abd deterioration due to plague, such as malaria and dengue. These diseases can leave permanent impact on internal organs. I will use myself as an example...
Magnetic imaging shows I have multiple cysts of my liver while I was hospitalized last December. Yet I have never consumed alcohol, did not smoke, use drugs, or abuse acetiminophen (tylenol) in my life. I spent a year and 4 months on the disease ridden Bassac River in Vietnam, and years in Mexico. Two confirmed cases of Dengue fever. In Oakland's Oak Knoll Naval Hospital, a fever sent me spiking at 105F. I am damaged goods. So, I must be extra cautious with quarantine. Children from third world countries make my base health index look insignificant.
If AstraZeneca's vaccine had a negative outcome of two individuals in 50,000 non placebo volunteer trials, the ratio is outrageous as compared to the outcome with COVID.
I have studied the AZ vaccine trials as much as AZ public announcements allow as well as independent research study conclusions. The amount of useful antigens and T cell response is clearly superior to most other vaccines. Sorry Moderna.
To spend 200,000 more lives waiting for CDC chasing ghosts involves me and my life. Let me sign a release of responsibilty form and let ME choose whether or not to allow inoculation. To argue with the likes of Pasteur et al is insane. The CDC mistargeted all three virus types last winter. I suffered for it.
The site you suggested Senor Fizz was a good read. Whether the AZ vaccine is miraculously approved just in time for the Moderna clinical approval announcement is yet to be seen. One of the vaccines has a heavy U.S. investor backing.
I spent 20 years successfully de-bunking fraudulent lead acid battery hyperbole. I was offered Seventy thousand dollars cash not check to endorse a brand name. I refused it. I would have refused a million dollars. With Covid vaccine to win or lose a profitable stock outcome is worth tens of billions of dollars. And after the college admissions scandal, call me doubtful David.
I hope and feel public peer pressure will emerge and save lives.
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MEXICOWANDERER
las peñas, michoacan, mexico
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About HSH | Subscribe
Center for Health Security
Today's Headlines: October 7, 2020
COVID-19
Clinical Practice
A Global Data Effort Probes Whether Covid Causes Diabetes (Wired) From Mohammad Shafi Kuchay, an endocrinologist who consulted on the cases, told WIRED via email that he and the other doctors assigned to the cases assumed the virus had somehow knocked out these patients’ insulin-making cells, giving them type 1 diabetes. And so the doctors put the men on a regimen of insulin injections. But as the months went by, they needed the injections less and less. They were shifted to oral antidiabetic drugs, and have been managing like this for more than two months now.
Public & Global Health
COVID-19 Vaccine May Be Ready By Year-end, Says WHO's Tedros (Reuters) A vaccine against COVID-19 may be ready by year-end, the head of the World Health Organization said on Tuesday. WHO Director-General Tedros Adhanom Ghebreyesus called for solidarity and political commitment by all leaders to ensure equal distribution of vaccines when they become available.
Iran to Require Face Masks in Capital as Virus Cases Hit High (Reuters) Iran will require face masks in public in the capital Tehran from Saturday, authorities said on Tuesday, announcing a daily record of 4,151 new coronavirus cases as hospitals face shortages of beds during a third wave of infections.
Backlash Grows in Orthodox Jewish Areas Over Virus Crackdown by Cuomo (New York Times) Orthodox Jewish and other religious leaders lashed out at Gov. Andrew M. Cuomo on Wednesday over new coronavirus restrictions on schools, businesses and houses of worship, as protests broke out in Brooklyn overnight, leading to scenes of chaos and the injury of at least one person.
COVID-SCORE: A Global Survey to Assess Public Perceptions of Government Responses to COVID-19 (COVID-SCORE-10) (PLOS One) The COVID-SCORE survey instrument demonstrated satisfactory validity. It may help governments more effectively engage constituents in current and future efforts to control COVID-19. Additional country-specific assessment should be undertaken to measure trends over time and the public perceptions of key aspects of government responses in other countries.
Global Shortage of Key Covid Drug Leads to NHS Rationing (The Guardian) A global shortage of remdesivir, one of the key Covid-19 drugs given to Donald Trump since he tested positive for the virus, is leading to rationing in the UK and pressure on the manufacturer to allow other companies to supply it. Remdesivir, made by the US company Gilead, is one of only two drugs proven to work against Covid-19. It has been shown to help patients recover faster from the disease and shorten the length of hospital treatment but is not a cure.
Science & Technology
Researchers Tout COVID-19 Testing Efficacy Innovation (Homeland Preparedness News) National Institute of Standards and Technology (NIST) researchers maintain they have developed a means of increasing primary SARS-CoV-2 virus testing sensitivity to help identify those who are asymptomatic.
Race for Covid-19 Vaccine Slows as Regulators, Top Warp Speed Official Tap the Brakes (STAT News) The race for a Covid-19 vaccine slowed on Tuesday, as both U.S. regulators and the head of the Trump administration’s Operation Warp Speed initiative tapped ever so softly on the brakes. The Food and Drug Administration released strengthened rules for authorizing any Covid-19 vaccine on an emergency basis. And Moncef Slaoui, co-chair of Operation Warp Speed, revealed that the government’s vaccine fast-tracking effort has urged manufacturers not to apply for emergency use authorization until they have significant amounts of vaccines to deploy.
See Also: FDA In Brief: FDA Issues Guidance on Emergency Use Authorization for COVID-19 Vaccines (FDA)
Eli Lilly Says its Monoclonal Antibody Cocktail is Effective in Treating Covid-19 (STAT News) Eli Lilly said Wednesday a monoclonal antibody treatment is effective in reducing levels of the virus that causes Covid-19 in patients, and also appears to prevent patients from visiting the emergency room or hospital.
Government Affairs & National Security
Government Scientist Adds To Whistle-Blower Complaint and Quits NIH (NPR) After a rocky, short-lived tenure at the National Institutes of Health, a former top federal scientist, who clashed with the Trump administration in the early days of the U.S. coronavirus outbreak, has stepped down from his post over what he said were continued efforts to thwart his work on the nation's pandemic response.
Medicine & Public Health
Newly Discovered Viruses Suggest ‘German Measles’ Jumped from Animals to Humans (Science) The virus that causes rubella, or German measles, finally has company. Scientists had never identified close relatives of the virus, leaving it as the only member of its genus, Rubivirus. But with a report in this week’s issue of Nature, rubella has gained a family. One of its two newfound relatives infects bats in Uganda; the other killed animals from three different species in a German zoo and was found in wild mice living nearby as well.
See Also: Relatives of Rubella Virus in Diverse Mammals (Nature)
Science & Technology
Pioneers of Revolutionary CRISPR Gene Editing Win Chemistry Nobel (Nature News and Comment) It’s CRISPR. Two scientists who pioneered the revolutionary gene-editing technology are the winners of this year’s Nobel Prize in Chemistry. The Nobel Committee’s selection of Emmanuelle Charpentier, now at the Max Planck Unit for the Science of Pathogens in Berlin, and Jennifer Doudna, at the University of California (UC), Berkeley, puts to rest years of speculation about who would be recognized for their work developing the CRISPR–Cas9 gene-editing tools.
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Rou222
USA
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I heard they made a vaccine in Russia...
has anyone heard about it?
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dturm
Lake County, IN
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Rou222 wrote:I heard they made a vaccine in Russia...
has anyone heard about it?
According to reports they have a vaccine but have skipped phase 3 trials before more wide spread use. The phase 3 trials are in place to better assess safety and efficacy. That is the phase many of the other vaccines in the world are in right now.
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