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Tennessee
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Having some limited experience in research one realizes how difficult it is to conduct 'valid' research. Trying to control all the dependent, and independent, variables, selecting samples and sizes to able to draw relatively, I say relatively, accurate conclusions and recommendations is NOT an easy task.
And, yes, unscrupulous, and uninformed, people will read a study, partially, and draw unfounded conclusions and/or extrapolate far beyond what the data reveals.
The majority of the time it is best to let those with the raw data, and necessary research skills, conduct the studies to their the best of their ability. Yes, at times mistakes will be made; very common in basic research, and the researchers learn from what doesn't work as much as what does work. There is a very small percentage of our population that possess strong research skills. We have to stay out of their way, support their funding, and have faith in their efforts. And, their research, in this case, centers around not only the medical side of this pandemic but also the 'preventative' side in terms of social behaviors.
Specifically we have to have faith they will come up with a vaccine as soon as possible and not work against their recommendations as we try to learn more and more.
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BCSnob
Middletown, MD
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Joined: 02/23/2002
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The United States Should Consider Compulsory SARS-CoV-2 Vaccination
Margaret Bove
Voices in Bioethics
May 4, 2020
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dturm
Lake County, IN
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I'm old enough to remember the first polio vaccine. We lined up at the local high school and got a shot (this was before the oral vaccine was developed). I had a friend who had a mild case, just a little weakness. Everybody wanted to get protection.
Unfortunately we have many who have forgotten, don't believe or have bought into the anti-vaccine propaganda. That is not to say that there are not risks to vaccination. If we get a safe, effective vaccine, this disease is bad enough that vaccination would be the lesser risk.
Doug & Sandy
Kaylee (16-year-old Terrier of some sort)
Winnie 4 1/2 year old golden
Sasha and many others at the Rainbow Bridge
2008 Southwind
2009 Honda CRV
Check out blog.rv.net
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NRALIFR
Let’s Go Girls! [End of Quote]
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Joined: 11/27/2005
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You won’t have to ask/tell me twice to get one.
I hope and pray every day for all the medical researchers that are working their tails off on cures and treatments. In the meantime, I do what we are all asked to do in order to slow the spread.
It’s my understanding though, that when the day comes that the FDA approves a SARS-CoV2 vaccine for use in humans, that will be the first time ever for a coronavirus. Is that a correct statement?
But, like many other things that have “never been done before”, there’s always a first time. I never cease to be amazed at man’s ability to overcome seemingly impossible problems.
![[emoticon]](http://www.coastresorts.com/sharedcontent/cfb/images/smile.gif "smile")
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dturm
Lake County, IN
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NRALIFR wrote:
It’s my understanding though, that when the day comes that the FDA approves a SARS-CoV2 vaccine for use in humans, that will be the first time ever for a coronavirus. Is that a correct statement?
There are coronavirus vaccines that we have in veterinary medicine. We routinely vaccinate dogs with one that causes an intestinal disease. There is one for FIP in cats that is not regularly given. There is a bovine coronavirus disease (also intestinal if I remember correctly - it's been about 50 years since that course) and a vaccine for it.
Doug, DVM
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MEXICOWANDERER
las peñas, michoacan, mexico
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#8 in the first Salk Beta trial Hayward, CA. March 1953. We were called "Pioneers". If a person needs "proof" just how reckless our immortal youth are, spend an hour on You Tube, and see the immortals performing some of the stupidest stunts imaginable. Covid? Masks? Distancing?
Be wary where young people may congregate
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NRALIFR
Let’s Go Girls! [End of Quote]
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Joined: 11/27/2005
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dturm wrote:NRALIFR wrote:
It’s my understanding though, that when the day comes that the FDA approves a SARS-CoV2 vaccine for use in humans, that will be the first time ever for a coronavirus. Is that a correct statement?
There are coronavirus vaccines that we have in veterinary medicine. We routinely vaccinate dogs with one that causes an intestinal disease. There is one for FIP in cats that is not regularly given. There is a bovine coronavirus disease (also intestinal if I remember correctly - it's been about 50 years since that course) and a vaccine for it.
Doug, DVM
Thank you Dr. Doug. That’s encouraging to hear. Perhaps cautious optimism for a human coronavirus vaccine is in order. I’m always interested in and appreciate your input on these subjects.
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BCSnob
Middletown, MD
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Joined: 02/23/2002
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I’ve seen news articles about the volunteers for these studies.
Human Challenge Studies to Accelerate Coronavirus Vaccine Licensure
Volunteers sign up to put their lives on the line for a coronavirus vaccine
These studies are routine for animal vaccines; they are used to determine effectiveness and duration of immunity.
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pasusan
Northernmost PA
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Joined: 05/13/2009
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I've been seeing more and more articles about the virus hanging on to some people. Folks seem to get better only to relapse over and over again. Here is one.
For folks who think this is just a flu and/or we should all just get it... I'm pretty nervous about the long-term implications.
"I'm out here to enjoy nature -- don't talk to me about the environment!" ~Denny Crane
Susan & Ben
2004 Roadtrek 170
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BCSnob
Middletown, MD
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Suppression of COVID-19 outbreak in the municipality of Vo, Italy
Quote:Abstract
On the 21st of February 2020 a resident of the municipality of Vo, a small town near Padua, died of pneumonia due to SARS-CoV-2 infection. This was the first COVID-19 death detected in Italy since the emergence of SARS-CoV-2 in the Chinese city of Wuhan, Hubei province. In response, the regional authorities imposed the lockdown of the whole municipality for 14 days. We collected information on the demography, clinical presentation, hospitalization, contact network and presence of SARS-CoV-2 infection in nasopharyngeal swabs for 85.9% and 71.5% of the population of Vo at two consecutive time points. On the first survey, which was conducted around the time the town lockdown started, we found a prevalence of infection of 2.6% (95% confidence interval (CI) 2.1-3.3%). On the second survey, which was conducted at the end of the lockdown, we found a prevalence of 1.2% (95% CI 0.8-1.8%). Notably, 43.2% (95% CI 32.2-54.7%) of the confirmed SARS-CoV-2 infections detected across the two surveys were asymptomatic.
The study tested a large percentage of the population twice. Small percentage of the sampled population was found to be infected. Of those infected, 40%-50% had no symptoms. The infectivity rate, R0, was estimated to be 3.0 (3 people infected by every sick person) at the start of the lockdown and decreased quickly to <1 during the lockdown.
* This post was
edited 07/02/20 11:07am by BCSnob *
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