BradW

Mayor of Flat Rock

Senior Member

Joined: 10/29/2001

View Profile

|
All is well. Must be a skinny needle because I never felt it. No reaction. Get the booster in 21 days. Pfizer. I see the light at the end of the tunnel.
Wake Up America
2019 Lance 1062 and 2018 F-350 CC PSD 4X4 DRW
Tembrens, Rear Roadmaster Sway Bar, Torklift 48" Extention and 30K Superhitch
Our New Lance 1062 Truck Camper Unloading at Dealer Photos
|
BCSnob

Middletown, MD

Senior Member

Joined: 02/23/2002

View Profile

|
Here is a preprint of a covid research article that spans two of my interests: science and dog training.
Scent trained dogs owned by the UAE Ministry of Interior were trained to detect the odor from SARS-CoV-2 positive patients using "sweat samples from symptomatic COVID-19 individuals (SARS-CoV-2 PCR positive) and from asymptomatic COVID-19 negative individuals (SARS-CoV-2 PCR negative".
After training these dogs were tested for sensitivity (aka accuracy) in a blinded study. 15 out of the 21 dogs trained achieved at 90% sensitivity in identifying the scents from Covid positive patients.
To put this into perspective, the RT-PCR test used to identify Covid positive patients has a reported sensitive of about 70%; meaning, the "gold standard" for identifying covid patients misses 30% of covid patients.
Source: Laboratory diagnosis of COVID-19 (Receiv........d 30 July 2020, Accepted 12 August 2020)
Quote: Use Of Canine Olfactory Detection For CO........U.A.E. Trained Detection Dog Sensitivity
This study aimed to evaluate the sensitivity of 21 dogs belonging to different United Arab Emirates (UAE) Ministry of Interior (MOI), trained for COVID-19 olfactory detection. The study involved 17 explosives detection dogs, two cadaver detection dogs and two dogs with no previous detection training. Training lasted two weeks before starting the validation protocol. Sequential five and seven-cone line-ups were used with axillary sweat samples from symptomatic COVID-19 individuals (SARS-CoV-2 PCR positive) and from asymptomatic COVID-19 negative individuals (SARS-CoV-2 PCR negative). A total of 1368 trials were performed during validation, including 151 positive and 110 negative samples. Each line-up had one positive sample and at least one negative sample. The dog had to mark the positive sample, randomly positioned behind one of the cones. The dog, handler and data recorder were blinded to the positive sample location. The calculated overall sensitivities were between 71% and 79% for three dogs, between 83% and 87% for three other dogs, and equal to or higher than 90% for the remaining 15 dogs (more than two thirds of the 21 dogs). After calculating the overall sensitivity for each dog using all line-ups, matched sensitivities were calculated only including line-ups containing COVID-19 positive and negative samples strictly comparable on confounding factors such as diabetes, anosmia, asthma, fever, body pain, diarrhoea, sex, hospital, method of sweat collection and sampling duration. Most of the time, the sensitivities increased after matching. Pandemic conditions in the U.A.E., associated with the desire to use dogs as an efficient mass-pretesting tool has already led to the operational deployment of the study dogs. Future studies will focus on comparatives fields-test results including the impact of the main COVID-19 comorbidities and other respiratory tract infections.
|
BradW

Mayor of Flat Rock

Senior Member

Joined: 10/29/2001

View Profile

|
A jeep riding buddy of mine died from covid last night. He was under 60, non-smoker and in pretty good shape. Real shame; he was a very nice person.
|
pianotuna

Regina, SK, Canada

Senior Member

Joined: 12/18/2004

View Profile

Offline
|
Just how effective are the vaccines?
-2021January22-[Future%7c+Button]]https:........letter]-2021January22-[Future%7c+Button]
Regards, Don
My ride is a 28 foot Class C, 256 watts solar, 556 amp-hours of Telcom jars, 3000 watt Magnum hybrid inverter, Sola Basic Autoformer, Microair Easy Start.
|
MEXICOWANDERER

las peñas, michoacan, mexico

Senior Member

Joined: 06/01/2007

View Profile

Offline
|
Sicker than a dawg. Fever and intestinal upset. I've always had post nasal drip so no clue there. I just don't have the strength to make it to the lab.
|
|
|
BradW

Mayor of Flat Rock

Senior Member

Joined: 10/29/2001

View Profile

|
pianotuna wrote: Just how effective?
I've read that one dose gives about 50% protection after 14 days....
Which ain't that great. After the second injection, it's about 95%. We get second shot 21 days from today.
|
BCSnob

Middletown, MD

Senior Member

Joined: 02/23/2002

View Profile

|
I would not put a lot of value on the estimated effectiveness of the vaccines after just one dose.
Quote: Pfizer-BioNTech
According to Pfizer data published in December 2020, the Pfizer-BioNTech vaccine is roughly 52% effective after the first dose. Out of 36,523 participants in the phase three trial – the final stage of testing where people either received two full doses, 21 days apart, or a placebo – who had no evidence of existing infection, 82 people in the placebo group and 39 in the vaccine group developed Covid-19 symptoms.
source: linked article above
(infection rate in unvaccinated - infection rate in vaccinated)/(infection rate in unvaccinated)
The article did not list number of participates that got the placebo vs those who got vaccinated; let's assume 18,261/18,262
infection rate of the unvaccinated = 0.45%
This number is used to estimate how many in the study were exposed to the virus (in the 21 days between the 1st and second dose). At this low level of exposure, I would not place a lot of value on the estimated vaccine effectiveness. Also we should keep in mind that protective antibodies don't develop immediately after vaccination; some of the infected in the vaccination group may have been infected before the vaccine had time to work.
|
Deb and Ed M

SW MI & Space Coast, FL USA

Senior Member

Joined: 06/07/2004

View Profile

|
MEXICOWANDERER wrote: Sicker than a dawg. Fever and intestinal upset. I've always had post nasal drip so no clue there. I just don't have the strength to make it to the lab.
Is there someone who can help you?? You need to treat the fever and stay hydrated!
|
Deb and Ed M

SW MI & Space Coast, FL USA

Senior Member

Joined: 06/07/2004

View Profile

|
I'm worried about Mexicowanderer....this was the last post he has made in days. Very health-compromised; and then posts that he's "sick as a dog" on the 22nd. I'm praying someone got him to a hospital...
|
silversand

Montreal

Senior Member

Joined: 09/12/2004

View Profile

|
Anyone hear from MexicoWanderer???
News on AstraZeneca production in Mexico and Brazil:
Its a full stop. A critical ingredient only available from China is now not available ( see SitRep (situational report) at Dr John Campbell's broadcast at 25:06 yesterday here--> )
Silver
2004 Chevy Silverado 2500HD 4x4 6.0L Ext/LB Tow Package 4L80E Michelin AT2s| Outfitter Caribou
|
|
|