BCSnob
Middletown, MD
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WHO “Solidarity” clinical trial for COVID-19 treatments
Quote:How the Solidarity Trial Works
Adults with COVID-19 admitted to participant hospitals can join this study. Eligible patients will be asked to sign to show they understand the possible risks and benefits and consent to joining the study. The medical team responsible for each patient will check whether any of the study treatments would definitely be unsuitable.
After those checks, brief identifying details and any other conditions are digitally recorded for the patient, who is then randomly allocated to one of the study options. This may or may not involve one of the study treatments. Neither the patient nor the medical staff choose which of the study options a patient will receive, as a computer makes this allocation at random.
Similar to a retrospective study. The randomization process does ensure equal sample sizes for each treatment within each hospital. What was not described by the WHO website were the doses and protocols used at the various hospitals participating in the trial which makes difficult to compare to other studies.
If hydroxychloroquine were an effective treatment it should be obvious in most studies. The medical research community should closely examine the differences in the various studies to determine the sources of the different results.
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Turtle n Peeps
California
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dturm wrote:
The fact that the WHO has suspended hydroxychloroquin studies has much more value when making informed decisions.
The same WHO that said in Jan 2020 the CV19 pandemic was just a "moderate global risk." That WHO?
Lets see how much "value in making informed decisions" the WHO had back in Jan.
~ Too many freaks & not enough circuses ~
"Life is not tried ~ it is merely survived ~ if you're standing
outside the fire"
"The best way to get a bad law repealed is to enforce it strictly."- Abraham Lincoln
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Moderator
Tennessee
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That was in Jan. All health agencies are learning more as to what doesn’t work and what does. And, more errors will be made and more learned. Basic research is more difficult than applied research.
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BCSnob
Middletown, MD
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Would you prefer the medical and public health leaders continue to promote what they were saying at the beginning of the pandemic or adjust their recommendations as they gain more knowledge about the virus?
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Turtle n Peeps
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BCSnob wrote:Would you prefer the medical and public health leaders continue to promote what they were saying at the beginning of the pandemic or adjust their recommendations as they gain more knowledge about the virus?
I would prefer they get all the facts and know what they are talking about before saying anything. (But that's just me)
I'm even ok with saying, "sorry, we can't release info because we don't know all the facts yet."
There is an old saying in race car racing and flying airplanes. "Guessing kills people."
The WHO was guessing back then.......and continue to do so.
In all fairness; so are a lot of Dr's.
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BCSnob
Middletown, MD
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If Hydroxichlroquine is such a great drug for the treatment of covid-19 why are so many good hospital systems and medical researchers having marginal success with this drug? Wouldn’t a great or even good drug be at least done what successful in the hands of most critical care systems?
And you would not complain as the WHO, CDC, etc simply said we don’t have all the answers right now so we won’t provide any recommendations to you on how to avoid getting sick or what is the best treatment if you do get sick? Even if you did not complain, government bodies that fund these organizations would simply say what are get getting from our funding.
You do understand that all the facts won’t be known until after the world population has achieved herd immunity.
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wing_zealot
East of the Mississippi
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BCSnob wrote:...You do understand that all the facts won’t be known until after the world population has achieved herd immunity. Then why are you so eager to dismiss any possible treatment as ineffective when all the facts won't be known for about another 9 months or more?
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BCSnob
Middletown, MD
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The unknown facts discussed above related to modes of transmission and recommendations for mask use and severity of the disease not effectiveness of drug treatments.
An effective drug should become obvious with the 1000s of patients that have been treated with this drug over the multiple drug trials.
If you’re sick with covid-19 would you want to wait the 5 days of treatment with this drug to see if you’re one of the lucky ones where it might show benefit or would you rather try one of the other possible treatments that are still being investigated?
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BCSnob
Middletown, MD
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This retrospective study using the same drug dosing regimen and similar number of patients as that n the Henry Ford study found no benefit from Hydroxychloroquine.
Observational Study of Hydroxychloroquine in Hospitalized Patients with Covid-19
This is a summary news article with links to the peer reviewed published studies showing no benefit for this drug.
Three big studies dim hopes that hydroxy........hloroquine can treat or prevent COVID-19
I’m still curious what was different in the Henry Ford study to show a benefit. But the bottom line is; if sick with covid I would not want to waist 5 or more days taking a drug with so many large studies where no benefit was found.
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Turtle n Peeps
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wing_zealot wrote:BCSnob wrote:...You do understand that all the facts won’t be known until after the world population has achieved herd immunity. Then why are you so eager to dismiss any possible treatment as ineffective when all the facts won't be known for about another 9 months or more?
I wondered the same thing. Very odd.
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