pianotuna

Regina, SK, Canada

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Mex,
The vaccine is a "best guess". They have been working on one that recognizes a part of the virus that does not change from strain to strain. That may be, at least for a while, a "universal" cure.
Regards, Don
My ride is a 28 foot Class C, 256 watts solar, 556 amp-hours of Telcom jars, 3000 watt Magnum hybrid inverter, Sola Basic Autoformer, Microair Easy Start.
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BCSnob

Middletown, MD

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Like all viruses the several strains of influenza A and B that are circulating mutate continually. Unlike most viruses, the mutations on the influenza viruses alter functional relative regions on the surface of the virus; regions that antibodies recognize. This is why each season people get sick (last years antibodies no longer are 100% effective) and why the vaccines are changed every year.
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dturm

Lake County, IN

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While what Mark says is accurate, there is some Cross-immunity when flu strains mutate.
Estimation of Cross-Immunity
Quote: We find that the cross-immunity between an influenza strain and the mutant that causes the next epidemic is 88%. Our method also gives estimates of the vaccine protection against the vaccinating strain, and the basic reproduction number of the 1968 pandemic influenza.
This study was one strain in one year but demonstrates the principle.
The amount of protection probably varies by mutation and year to year, but along with vaccinations against the flu account for the fact that we don't have flu pandemics every year.
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MEXICOWANDERER

las peñas, michoacan, mexico

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https://en.wikipedia.org/wiki/Spanish_flu
Above is the synopsis of the 1918 influenza pandemic. It is not a fun read. My grandmoter sparked my interests in the early 1970's about how she, pregnant with my father, fled to a pioneer cabin in 1918 at Jack Creek, MT, which I subsequently visited in 1972. A 3-room lodgepole pine affair with an outbuilding downhill and a spring uphill. A timber and earth, root cellar provided storage for venison, elk and root vegetables including carrots, potatoes, sweet potatoes, rutabagas, turnips, etc. Through sheer blundering, I met my grandmother's midwife in 1972 in Ennis MT.
Of particular interest in the WIKI account are the associations of same type (H1N1, H3N2) recent flu bouts with huge outbreaks a year or two later. Since I fared poorly early this year first with H3N2 then H1N1, both leaving me bedridden (16 long days with the H1N1) I have wondered if the addociation between the illnesses and my month long bout with loss of smell in July (choked on but could not smell pure propane or detect aftershave) had anything to do with it. The afternoon fevers ranging to 101F lasting a month are also a mystery.
The occurance of Cytokine Storms in 1918 raised my eyebrows, as did the rise of ANTI MASK REBELLION in San Francisco.
But the WIKI article was an eye-opener for me. I can only guess that by now the article has undergone somewhat of a peer review.
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MEXICOWANDERER

las peñas, michoacan, mexico

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The Chief Officer of AstraZeneca appeared yesterday to clarify an obvious mistake announcement made by one of his laboratory executives which apparently resulted in a public uproar.
Wipe clean everything you've heard. If clearence is given, health care workers will be given top priority. Then law enforcement and government. Then dangerously compromised seniors with health problems.////// And finally the general public. There are 2 dosis of this brand of medication which is probably going to be first on the market, but delayed until other manufacturers are ready with their brand of vaccines. Some of which need but one dose. *I guess* the rationale for early inoculations for the most vulnerable elderly is because if the company waits until the general release date, hundreds maybe thousands of the most vulnerable may die or clog up ICU facilities? The CEO also said they are targeting "near Christmas" for the first emergency personnel inoculations.
Mexico has a huge AstraZeneca plant near Mexico City. If a miracle happens and I get inoculated very early. I will maintain a heavily abbreviated daily journal of facts like temperature, pain, swelling, taste, smell, etc. And impressions. I have had some nasty secondary reactions to "senior grade flu inoculations" so I am not going to assume post inoculation reaction to the covid19 vaccine will be a cake walk.
Part of the public negative reaction to the Covid19 irritation is the extremely fluid and changing dates from different manufacturers. Down here it is abnormal to have fixed and adhered to dates and times (limited to bull fights and bus schedules)
When I see gov't data online about plunging hospital admissions and fatalities, then I will relax a little.
There is no question that the AstraZeneca vaccine will be released down here first. The cross-border virus flares guarantees it.
If that's the case, I'll do my best to post accurate relavent information.
Pablo and I went north last week. When I furnished information that he was driving me north to a cardiologist's appt for my pacemaker they let him enter. He has a current USA visitor's card. Only green card workers are allowed unrestricted passage.
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qtla9111

Monterrey, Mexico

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CanSinoBio will be testing their vaccine on 10,000 Mexicans in the coming weeks. Mexico refuses to purchase vaccines from a Mexican provider stating that they are monopolies and the government won't give in to corruption. Mexico will purchase from overseas at an increase of 15% over Mexican drug manufacturers.
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pianotuna

Regina, SK, Canada

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Mex,
The vaccine you have mentioned does cause a fever of 104 f (40 c)
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MEXICOWANDERER

las peñas, michoacan, mexico

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Hi Sasquatachewan Don ![smile [emoticon]](http://www.coastresorts.com/sharedcontent/cfb/images/smile.gif)
Oxford University says no to high fevers for seniors. As a matter of fact their tight control studies show far fewer side effects for >60 years than for younger folks. I have no idea how they managed that. AztraZeneca considers a 40c fever to to be a danger in itself to elderly. Cardiorespiratory issues. If you have any links re AZ and side effects please share them.
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pianotuna

Regina, SK, Canada

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Hi Mex(ican jumping bean),
It was a radio report I heard from CBC which is usually considered a reliable source.
Here is a source https://www.theguardian.com/world/2020/s........ne-trial-participant-undeterred-by-pause
and a quote:
"Before receiving the first vaccine dose, he had been warned that he may feel pain at the site of the injection and a fever for a few days, both of which he experienced. But three days after the fever subsided it returned, he said, and his temperature reached 39.4C (103F)."
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Moderator

Tennessee

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We just want to thank you, members, for keeping this topic 'on topic' and trying your best to use reliable sources rather than a lot of the non-sense that has been in the news. Some lives may depend on what is read here! We still have a long way to go to beat this thing and it is going to require we ALL work together toward that end.
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