BCSnob

Middletown, MD

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Covid antibody testing in a school system in Chili
SARS-CoV-2 antibody prevalence in blood in a large school community subject to a Covid-19 outbreak: a cross-sectional study
The school system was preschool through high school.
38% of the students were tested evenly distributed by class.
74% of the staff were tested
Almost 10% of the tested students were positive for covid antibodies.
Almost 17% of the staff were positive
There was a higher percentage of positive students in the lower grades than in high school. Up to 25% of the students in a primary classroom were positive when the teacher was also positive.
Quote: The most common Covid-19 contact in antibody positive (versus negative) children was their teacher (21% vs. 12%; P= 0.022), a household relative (11% vs. 2%; P<0.001), a classmate (9 % vs. 4%; P= 0.03), followed by a home caregiver (4% vs. 0.1%; P<0.001). Sources with the greatest likelihood of possible contagion in students were: a home caregiver (OR: 27.9), a household relative (OR: 5.4), a classmate (OR: 3.2), and teacher (OR: 2.2).
* This post was
edited 07/13/20 02:11pm by BCSnob *
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BCSnob

Middletown, MD

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This is a very informative and concise review of the current state of knowledge on Covid-19.
Pathophysiology, Transmission, Diagnosis........t of Coronavirus Disease 2019 (COVID-19)
July 10, 2020
Below are a few quotes I found especially informative.
Quote: Transmission17 of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) occurs primarily via respiratory droplets from face-to-face contact and, to a lesser degree, via contaminated surfaces. Aerosol spread may occur, but the role of aerosol spread in humans remains unclear. An estimated 48% to 62% of transmission may occur via presymptomatic carriers.
Quote: The mean (interquartile range) incubation period (the time from exposure to symptom onset) for COVID-19 is approximately 5 (2-7) days.43,44 Approximately 97.5% of individuals who develop symptoms will do so within 11.5 days of infection.43 The median (interquartile range) interval from symptom onset to hospital admission is 7 (3-9) days.45 The median age of hospitalized patients varies between 47 and 73 years, with most cohorts having a male preponderance of approximately 60%.44,46,47 Among patients hospitalized with COVID-19, 74% to 86% are aged at least 50 years.45,47
Quote:
Although only?approximately?25% of infected patients have comorbidities, 60% to 90% of hospitalized infected patients have comorbidities.45-49 The most common comorbidities in hospitalized patients include hypertension (present in 48%-57% of patients), diabetes (17%-34%), cardiovascular disease (21%-28%), chronic pulmonary disease (4%-10%), chronic kidney disease (3%-13%), malignancy (6%-8%), and chronic liver disease (<5%).45,46,49
Quote: Several serological tests can also aid in the diagnosis and measurement of responses to novel vaccines.62,65,66 However, the presence of antibodies may not confer immunity because not all antibodies produced in response to infection are neutralizing.
Quote: More than 200 trials of chloroquine/hydroxychloroquine, compounds that inhibit viral entry and endocytosis of SARS-CoV-2 in vitro and may have beneficial immunomodulatory effects in vivo,79,80 have been initiated, but early data from clinical trials in hospitalized patients with COVID-19 have not demonstrated clear benefit.81-83
Quote: A clinical trial of 150 patients in China admitted to the hospital for mild to moderate COVID-19 did not find an effect on negative conversion of SARS-CoV-2 by 28 days (the main outcome measure) when compared with standard of care alone.83
Quote: Are masks effective at preventing spread?
Yes. Face masks reduce the spread of viral respiratory infection. N95 respirators and surgical masks both provide substantial protection (compared with no mask), and surgical masks provide greater protection than cloth masks. However, physical distancing is also associated with substantial reduction of viral transmission, with greater distances providing greater protection. Additional measures such as hand and environmental disinfection are also important.
* This post was
edited 07/14/20 06:12am by BCSnob *
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pianotuna

Regina, SK, Canada

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Hi,
I'm sorry to say that Regina lost its zero covid status. We went for 25 days--but then one plane came in from Vancouver and another from Toronto. Each plane had an active case. So now the other passengers have been asked to self quarantine, and tracking of their contacts has begun.
We went from zero to five cases literally overnight.
Folks here have become complacent about masks. The last time I was in a grocery store I only saw one other person wearing a mask. Yes, the risk may be lower, but it is not zero and won't be for some time.
Regards, Don
My ride is a 28 foot Class C, 256 watts solar, 556 amp-hours of Telcom jars, 3000 watt Magnum hybrid inverter, Sola Basic Autoformer, Microair Easy Start.
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MEXICOWANDERER

las peñas, michoacan, mexico

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https://ard.bmj.com/content/79/5/667.full
Fascinating reading
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MarkieBob

Mt. Vernon, WA

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I just found this thread on covid. I see it's up to 40 pages long now. Lots of comments and concerns here I'm sure. BUT, how does a guy read all 40 pages and find anything of interest to them? I guess I'm rambling, but it seems too long and maybe could be broken down to specific items in the covid general topic? Maybe add a main category on covid (like Class A motorhomes, etc.) and break it down from there? Just a suggestion. I don't see me reading all 40 pages--which is maybe my laziness or time factor considered. Just wondering.......
2011 Holiday Rambler Vacationer Class A
2004 Suzuki Grand Vitara toad.
2006 Ford F350 PSD 6.0 4x4
1990 18' Seaswirl boat
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BCSnob

Middletown, MD

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Joined: 02/23/2002

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Have you read the first post which was by the moderator?
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MEXICOWANDERER

las peñas, michoacan, mexico

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Want a quicker verified source of info?
Peruse the pages of Johns Hopkins, which is an oft-quoted peer-reviewed source3 of information.
The world has never faced a medical challenge like this virus. The best of the best have to make life and death decisions without medical precedents to help them. The seeming sole positive is that once this is resolved it may prove to serve as a guidepost to manage other yet to be controlled viruses.
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cptqueeg

Idaho

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Joined: 04/11/2020

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Kids and school-
"“So long as children are not just a complete dead end — incapable of passing the virus on, which does not seem to be the case — putting them together in schools, having them mix with teachers and other students will provide additional opportunities for the virus to move from person to person,” he said."
Text above from this article-
https://www.nytimes.com/2020/07/18/health/coronavirus-children-schools.html?smid=em-share
Article based on this study published by CDC-
https://wwwnc.cdc.gov/eid/article/26/10/20-1315_article
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BCSnob

Middletown, MD

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Joined: 02/23/2002

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Oxford's COVID-19 Vaccine Candidate Take........Forward, Showing Success in Early Trials
The Time article has a link to the publication in Lancet. My employer has developed antibody test for SARS-cov-2 and it was used in the Oxford vaccine phase 1/2 trial.
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edited 07/20/20 12:47pm by BCSnob *
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wilber1

Abbotsford B.C.

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Joined: 12/16/2002

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Turtle n Peeps wrote: BCSnob wrote: Would you prefer the medical and public health leaders continue to promote what they were saying at the beginning of the pandemic or adjust their recommendations as they gain more knowledge about the virus?
I would prefer they get all the facts and know what they are talking about before saying anything. (But that's just me)
I'm even ok with saying, "sorry, we can't release info because we don't know all the facts yet."
There is an old saying in race car racing and flying airplanes. "Guessing kills people."
The WHO was guessing back then.......and continue to do so.
In all fairness; so are a lot of Dr's.
You don't think the people who built and flew the first aircraft engaged in a some guess work?
"Never trust a man who has not a single redeeming vice" WSC
2011 RAM 3500 SRW
2015 Grand Design Reflection 303RLS
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